The competition was contested by the 36 member clubs of the Northern Ireland Football League, commencing on 6 August 2022 with the preliminary round and concluding with the final on 12 March 2023.
Coleraine finished as runners-up for the second consecutive season after their seventh defeat in a League Cup final overall.
The competition was open to the 36 members of the Northern Ireland Football League (NIFL).
The top 16 league clubs from the previous season were seeded in this round in order to avoid drawing each other.
[2][3] Annagh United (2) Ballinamallard United (2) Ballymena United (1) Carrick Rangers (1) Cliftonville (1) Coleraine (1) Crusaders (1) Dungannon Swifts (1) Glenavon (1) Glentoran (1) Larne (1) Linfield (1) Loughgall (2) Newry City (1) Portadown (1) Warrenpoint Town (2) Ards (2) Armagh City (3) Ballyclare Comrades (2) Banbridge Town (3) Bangor (3) Dergview (2) Dollingstown (3) Dundela (2) Harland & Wolff Welders (2) Institute (2) Knockbreda (2) Limavady United (3) Lisburn Distillery (3) Moyola Park (3) Newington (2) Portstewart (3)