PSV participated in the Eredivisie, KNVB Cup, Johan Cruyff Shield, UEFA Champions League and UEFA Europa League.

Win Draw Loss Fixtures Source: Soccerway Source: Eredivisie The league fixtures were announced on 17 June 2022.

[30] The draw for the third qualifying round was held on 18 July 2022.

The draw for the play-off round was held on 2 August 2022.

The knockout round play-offs draw was held on 7 November 2022.