The 2022–23 season was the 95th in the history of Real Valladolid and their first season back in the top flight.

The club participated in La Liga and the Copa del Rey.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Fixtures Source: Soccerway Source: La Liga The league fixtures were announced on 23 June 2022.