The 2022–23 season was the 116th season in the history of SC Paderborn and their third consecutive season in the second division.

Bundesliga and the DFB-Pokal.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Win Draw Loss Fixtures Source: Soccerway Source: DFB The league fixtures were announced on 17 June 2022.