The 2022–23 SMU Mustangs men's basketball team represented Southern Methodist University during the 2022–23 NCAA Division I men's basketball season.

The Mustangs were led by first-year head coach Rob Lanier and played their home games at Moody Coliseum on their campus in University Park, Texas as members of the American Athletic Conference.

They defeated Tulsa in the quarterfinals of the AAC tournament before losing to Memphis in the semifinals.

They received an at-large bid to the National Invitation Tournament as a No.

[1] On March 27, the school named Georgia State head coach Rob Lanier the team's new head coach.