The league consisted of 16 teams: seven teams from the previous season, one team relegated from 2021–22 Serbian SuperLiga, five new teams promoted from Serbian League and Novi Sad 1921 who was merged with Proleter Novi Sad.
Each time will play each other twice in round-robin format after which top half will play in Promotion round and bottom half in Relegation round Play-offs.
First two teams from the Promotion round will be promoted to next season of Serbian Superliga, while third and fourth team will play in a Promotion Play-off.
The top eight teams advanced from the regular season.
The bottom eight teams advanced from the regular season.