[1] The Melbourne Boomers were the defending champions, but were defeated in the Semi-Finals by Southside.
[2] The Townsville Fire won their fourth championship title after sweeping Southside, 2–0 in the Grand Final series.
[4] Spalding again provided equipment including the official game ball, alongside iAthletic supplying team apparel for the sixth consecutive season.
In June 2022, the season structure was confirmed to feature an 84-game regular season and best-of-three Semi-Final & Grand Final series' to follow.
[5] The WNBL later announced in September 2022 that a new broadcast deal had been signed with the 9Now and ESPN for the upcoming season.