The 2022–23 Xavier Musketeers men's basketball team represented Xavier University during the 2022–23 NCAA Division I men's basketball season as a member of the Big East Conference.

Led by Sean Miller in the first season of his second stint after coaching the Musketeers from 2004 to 2009, they played their home games at the Cintas Center in Cincinnati, Ohio.

The team received an at-large bid to the NCAA Tournament, where they defeated Kennesaw State and Pittsburgh to advance to the Sweet Sixteen for the first time since 2017.

The team received an at-large bid to the National Invitation Tournament where they defeated Cleveland State, Florida, Vanderbilt, and St. Bonaventure to advance to the championship game.

Head coach Travis Steele was fired on March 16, 2022, the day after the first win in the NIT.