The 2022 African U-20 Women's World Cup Qualifying Tournament was the 11th edition of the African U-20 Women's World Cup Qualifying Tournament, the biennial international youth football competition organised by the Confederation of African Football (CAF) to determine which women's under-20 national teams from Africa qualify for the FIFA U-20 Women's World Cup.

Players born on or after 1 January 2002 were eligible to compete in the tournament.

Two teams could qualify from this tournament for the 2022 FIFA U-20 Women's World Cup (originally 2020 but postponed due to COVID-19 pandemic) in Costa Rica as the CAF representatives.

[1] This edition of the tournament also doubles as the qualifiers for the 2023 African Games in Accra, Ghana where teams who reached the fourth round qualified automatically.

A total of 40 (out of 54) CAF member national teams entered the qualifying rounds.

The draw was held on 10 May 2021 at the CAF headquarters in Cairo, Egypt.

[2] Qualification ties were played on a home-and-away two-legged basis.

If the aggregate score was tied after the second leg, the away goals rule would be applied, and if still tied, the penalty shoot-out (no extra time) would be used to determine the winner.

The following two teams from CAF qualified for the 2022 FIFA U-20 Women's World Cup.