Qualification for the 2022 CAF Women's Champions League began on 7 August and concluded on 15 September 2022.
All participating teams qualified for the qualification phase via winning their respective national league titles and had their club licensing applications accepted by CAF.
Seven clubs competed for this year's qualification tournament which was held in Yamoussoukro, Ivory Coast, from 20 August to 2 September 2022.
Qualification from this region was originally to be held from 20 August to 4 September 2022 in Yaoundé, Cameroon, with two-legged ties for the semi-finals.
Qualification from this region (branded as the COSAFA Women's Champions League) was held in South Africa from 7 to 14 August 2022.