The 2022 Club Deportivo Universidad Católica season is the 82nd season and the club's 48th consecutive season in the top flight of Chilean football.

In addition to the domestic league, Universidad Católica are participating in this season's editions of the Copa Chile, the Supercopa de Chile, and the Copa Libertadores.

Last updated: 7 July 2022 Source: Soccerway Source: Primera Division The draw for the group stage was held on 25 March 2022, 12:00 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay.

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Last updated: 25 June 2022Source: Soccerway † Player left Universidad Católica during the season