[1][2][3] The election were won by the Spolu alliance consisting of the Civic Democratic Party (ODS), KDU-ČSL and TOP 09 which won 20 seats (including Tábor 2020 candidate Marek Slabý and ProMOST candidate Jan Paparega).

[5] Among the incumbent senators, Anna Hubáčková, Jiří Cieńciała, Jan Žaloudík, Petr Šilar and Jaroslav Doubrava did not run.

[17] ANO 2011 launched campaign on 5 September 2022 with party leader Andrej Babiš appealed to voter to make the election a referendum about Petr Fiala's cabinet.

3 candidates were elected in the first round including Jiří Růžička, Petr Fiala and Ladislav Václavec.

Party lost some of its significant politicians such as Jan Horník, Petr Holeček or Václav Chaloupek who failed to advance for second round.

[25] Party leadership went to the district to personally support Nagyová against Vystrčil whose defeat would weaken government coalition.

[34] Prime Minister Petr Fiala stated after election that the result is a success for Spolu.

He stated that he is especially pleased with Jihlava district result which he considers personal defeat for Andrej Babiš.

[36] Several political scientists including Terezie Wasserbauerová or Jan Tvrdoň attributed defeat of ANO 2011 in second round to a bad strategy by party leadership which wanted to make the election a referendum about governing coalition and focused campaign in Jihlava district and not in districts where the race was expected to be close.

[37][38] Kamil Švec noted that ANO is losing Senate elections repeatedly in second round.