16 teams competed, with the winner representing Donegal in the Ulster Senior Club Football Championship.
Naomh Conaill advanced again, to the 2022 final, where the club won this time, but in controversial circumstances, and by one point, after St Eunan's player Shane O'Donnell was sent off for patting Jeaic Mac Ceallabhuí.
The draw was held on Tuesday evening, 21 June, at the Abbey Hotel in Donegal Town.
[7] Four round-robin games for all clubs was the format, then the group standings amalgamated to decide on the competition's quarter-finalists.
[56] The first quarter-final[57] ended with Cill Chartha defeating Na Cealla Beaga 1–14 to 1–7 at Tír Chonaill Park.
[57][61][62] The other two quarter-finals saw Gaoth Dobhair emerge with a one-point (0–8 to 0–7) win against Aodh Ruadh at Fintra,[57][63] while Naomh Conaill defeated Glenswilly by 2–10 to 0–10 at O'Donnell Park.
[65] The first semi-final — between Cill Chartha and St Eunan's — was scheduled for 20:00 on Saturday 24 September at MacCumhaill Park, and to be streamed live (pay-per-view) on Donegal GAA TV, while the second semi-final — between Gaoth Dobhair and Naomh Conaill — was scheduled for 16:00 on Sunday 25 September also at MacCumhaill Park, and also to be streamed live (pay-per-view) on Donegal GAA TV.
[66] However, the first semi-final was postponed until the following weekend, due to bereavements (the father and sister of Brendan Devenney had both died, suddenly, and separately).
[68] St Eunan's defeated Cill Chartha by 1–13 to 1–11 in the other semi-final, with both victors qualifying for the 2022 championship final.
[1] Naomh Conaill won this one, but in controversial circumstances, and by one point, after St Eunan's player Shane O'Donnell was sent off for patting Jeaic Mac Ceallabhuí.
[66] Ard an Rátha v St Naul's was played at Eamonn O'Broinn Memorial Park from 13:00, and streamed live (pay-per-view) on Donegal GAA TV; Milford v Réalt na Mara was played at Páirc Aodh Rua from 13:30, and streamed live (and available for free) on Donegal Facebook.
[2] On 12 December 2022, Brendan McDyer was named as the recipient of the annual Gradam Shéamuis Mhic Géidigh.