[1] On 10 March, Amirbek Juraboev left Istiklol to join United City in the Philippines Football League.

[4] On 31 March, Istiklol announced the signings of Nuriddin Davronov, Eric Bocoum, Nikita Chicherin, Uladzislaw Kasmynin, Temur Partsvania, Mukhammad Isaev, Sayedi Kovussho, Mukhammadzhon Rakhimov, Tabrezi Davlatmir and Alidzhon Karomatullozoda.

[6] On 27 June, Vitaly Levchenko and his coaching staff left Istiklol after their contracts expired,[7] with Assistant Manager Alisher Tukhtaev being placed in interim charger.

[9] On 2 August, Istiklol announced that Rustam Soirov had left the club to join Levadia Tallinn on a three-year contract.

[10] The following day, 3 August, Istiklol announced the signings of Gonzalo Ritacco, Siyovush Asrorov, Idriss Aminu, Hlib Hrachov and Parviz Baki-Akhunov.