The Women's 100 metre freestyle competition of the 2022 FINA World Swimming Championships (25 m) was held on 14 and 15 December 2022.

[1] Prior to the competition, the existing world and championship records were as follows.

The following new records were set during this competition: The heats were started on 14 December at 11:41.

[2] The semifinals were started on 14 December at 19:57.

[3] The final was held on 15 December at 19:42.