The Women's 50 metre butterfly competition of the 2022 FINA World Swimming Championships (25 m) was held on 13 and 14 December 2022.

[1] Prior to the competition, the existing world and championship records were as follows.

The heats were started on 13 December at 11:59.

[2] The semifinals were started on 13 December at 19:45.

[3] The final was held on 14 December at 21:14.