David Goffin defeated Alex Molčan in the final, 3–6, 6–3, 6–3 to win the singles tennis title at the 2022 Grand Prix Hassan II.

It was Goffin's sixth ATP singles title.

[1] Benoît Paire was the defending champion from when the event was last held in 2019,[2] but withdrew before the beginning of the tournament.

[3]