The 2022 Louisiana Ragin' Cajuns football team represented the University of Louisiana at Lafayette in the 2022 NCAA Division I FBS football season.

The Ragin' Cajuns played their home games at Cajun Field in Lafayette, Louisiana, and competed in the West Division of the Sun Belt Conference.

They were led by first-year head coach Michael Desormeaux.

The Cajuns were picked to finish first in the West Division and first in the conference.

Roster Last update: 5 September 2022 All conference games were announced in early March 2022.