2022 Mexican League season

It was contested by 18 teams, evenly divided in North and South zones.

The season started on 21 April with the series between the defending champions Toros de Tijuana and Diablos Rojos del México and ended on 19 September with the last game of the Serie del Rey, where Leones de Yucatán defeated Sultanes de Monterrey to win the championship.

Tecolotes de los Dos Laredos won the series, 4–1.

Diablos Rojos del México won the series, 4–0.

Diablos Rojos del México won the series, 4–0.