The 2022 Missouri State Bears football team represented Missouri State University as a member of the Missouri Valley Football Conference (MVFC) during the 2022 NCAA Division I FCS football season.

They were led by third-year head coach Bobby Petrino and played their home games at Robert W. Plaster Stadium in Springfield, Missouri.

The media picked the Bears to finish in 3rd place.

Missouri State had eight players selected to the 2022 All-MVFC Preseason Team.

Preseason All-MVFC Team Award Watch Lists Source:[6] Quarterback Running back Wide receiver Tight end Punter Offensive lineman Defensive lineman Long snapper Linebacker Cornerback Safety Placekicker Source:[7] Last updated: August 18, 2022.