The Alouettes finished second in their division, an improvement on their third place finish in 2021 and qualified for the playoffs for the third consecutive season following the team's week 19 victory over the Ottawa Redblacks.

The Alouettes held their training camp in Trois-Rivières at Stade Diablos.

[3] However, he was fired after four games on July 6, 2022, where the team started with a 1–3 record.

[5] The Alouettes also fired their defensive coordinator and defensive backs coach, Barron Miles, on July 6, 2022, and he was replaced by Noel Thorpe, who returned for his third stint with the club.

[9] The team also acquired the ninth overall selection from the Winnipeg Blue Bombers after trading Cameron Lawson.