The 2022 Nicholls Colonels baseball team represented Nicholls State University during the 2022 NCAA Division I baseball season.

The Colonels played their home games at Ben Meyer Diamond at Ray E. Didier Field and were led by first–year head coach Mike Silva.

They were members of the Southland Conference.

The Southland Conference Coaches Poll was released on February 10, 2022 and the Colonels were picked to finish tied for seventh in the conference with 24 votes.

[2] [3] Mike Silva (East Central) Ladd Rhodes (Southern Mississippi)Cody Livingston (Southern Mississippi)Gabe Woods (Southeastern Louisiana) Roster Last update: 12 April 2022 *Rankings are based on the team's current ranking in the D1Baseball poll.