Defending champion Ken Skupski and his partner, Jonny O'Mara, defeated Julian Cash and Henry Patten in the final, 3–6, 6–2, [16–14], to win the men's doubles tennis title at the 2022 Nottingham Open.

[1] The third seeds saved three championship points en route to the title.

Skupski had won the title in 2021 with Matt Reid,[2] but Reid did not return to compete.