The 2022 O Gran Camiño (English: The Great Way) was a road cycling stage race that took place from 24 to 27 February 2022 in the autonomous community of Galicia in northwestern Spain.

The race was rated as a category 2.1 event on the 2022 UCI Europe Tour calendar, and was the inaugural edition of O Gran Camiño.

[3][4] All but three teams entered a full squad of seven riders; Cofidis, EF Education–EasyPost, and Human Powered Health each entered six riders.

[5] With one late non-starter, Atum General / Tavira / AP Maria Nova Hotel was reduced to six riders.

In total, 115 riders started the race, of which 109 finished.