2022 Odlum Brown Vancouver Open – Women's singles

Heather Watson was the defending champion from when the tournament was last held in 2019 as part of the ITF Women's World Tennis Tour, [1] but lost in the second round to Chloé Paquet.

Valentini Grammatikopoulou won the title, defeating Lucia Bronzetti in the final, 6–2, 6–4.

[2]