The 44th PBA Philippine Cup started on June 5 and ended on September 4, 2022.

The tournament did not allow teams to hire foreign players or imports.

The following format will be observed for the duration of the conference: San Miguel has the twice-to-beat advantage; they have to be beaten twice, while their opponents just once, to advance.

TNT has the twice-to-beat advantage; they have to be beaten twice, while their opponents just once, to advance.

The two finalists also qualify to the 2022–23 East Asia Super League season.