Coached by Brad Arthur and co-captained by Clinton Gutherson and Junior Paulo, they competed in the NRL's 2022 Telstra Premiership.

Although the club finished within the top four, many pundits and experts wrote off Parramatta's premiership chances.

In week one of the finals, Parramatta were beaten 27-8 by Penrith with Mitchell Moses being taken off injured in the second half.

Parramatta headed into the game as outsiders but pulled off one of the biggest upsets in 2022 and NRL finals history defeating North Queensland 24–20.

In the 2022 NRL Grand Final, Parramatta played against fellow Western Sydney club Penrith.