[1] This was the first time Worlds was in Mexico since 2000, when it was also held in San Luis Potosi.

The 2022 World Championships used a best of five games match format with each game to 11 points, win by 2, with rally scoring, as used in other sports like squash and volleyball.

Previously, racquetball games used side-out scoring, where players scored points only when they had won a rally which began with that player serving.

In 2022, Mexicans Paola Longoria and Samantha Salas won Women's Doubles for a record extending 5th time, but they needed five games and extra points in the fifth game to defeat the Argentina team of Valeria Centellas and Natalia Mendez in the final, winning 11–6, 15–17, 11–9, 9–11, 12–10.

Initially, players competed in separate groups over three days.