The 2022 Rugby Championship was the tenth edition of the annual southern hemisphere competition, involving Argentina, Australia, New Zealand and South Africa.

Note: Ages, caps and clubs/franchises are of 6 August 2022 – the starting date of the tournament On 21 July, Argentina announced a 34-man squad for the Rugby Championship.

On 14 August, Eduardo Bello, Bautista Delguy, Guido Petti and Santiago Socino joined the squad ahead of their tour to New Zealand in rounds 3 & 4.

On 18 August, Bernard Foley and Langi Gleeson was added to the squad for Australia's round three and four matches against South Africa.

On 26 July, Fletcher Newell was called into the squad as a replacement for Ofa Tu'ungafasi who suffered a neck injury after the Steinlager Series.