The Roughriders were eliminated from post-season contention on October 22, 2022, following a loss to the Calgary Stampeders.
[2] The Roughriders selected fifth in each round of the snake draft.
[4] The Roughriders had the seventh selection in each of the eight rounds of the draft after losing the West Final and finishing second in the 2021 league standings.
[5] [6][7][8] The Roughriders played in a neutral site game against the Toronto Argonauts who was the home team for their Week 6 match-up.
[9] It was confirmed on March 24, 2022, that the game would be played in Wolfville, Nova Scotia at Raymond Field as part of the Touchdown Atlantic series.