[2] The top three teams qualified for the 2022 FIFA U-17 Women's World Cup in India as the CONMEBOL representatives.

[3] Defending champions Brazil won their fourth title after finish first in the final stage and alongside the runners-up Colombia and third place Chile qualified for the 2022 FIFA U-17 Women's World Cup.

The remaining eight teams were split into four "pairing pots" (Colombia–Venezuela, Chile-Paraguay, Argentina-Peru, Ecuador-Bolivia) based on the final placement they reached in the last played edition of the tournament (shown in brackets).

[8] The draw resulted in the following groups:[9] On 4 February 2022, CONMEBOL informed to its member associations the referees appointed for the tournament.

If tied on points, tiebreakers are applied in the following order (Regulations Article 20):[11] The top two teams of each group advance to the final stage.