[1][2] The top two teams of the tournament qualified for the 2022 FIFA U-20 Women's World Cup in Costa Rica as the CONMEBOL representatives.

Brazil successfully retained their title and won their ninth in a row after finish first in the final stage and alongside the runners-up Colombia qualified for the 2022 FIFA U-20 Women's World Cup.

Chile was named as host country of the tournament at the CONMEBOL Council meeting held on 27 October 2021.

The remaining eight teams were split into four "pairing pots" (Paraguay-Colombia, Venezuela-Ecuador, Argentina-Uruguay, Peru-Bolivia) based on the final placement they reached in the 2018 edition of the tournament (shown in brackets).

If tied on points, tiebreakers are applied in the following order (Regulations Article 20):[8] The top two teams of each group advance to the final stage.