The deadline for nominations was August 19, 2022, at 2 p.m.[1] 31 candidates ran to be Mayor of Toronto including incumbent John Tory, seeking a third term,[2] and prominent urbanist Gil Peñalosa.

[17][10] Rose Milczyn was appointed by council to serve the remainder of Ford's term and is not running in the election.

[12] Incumbent city councillor Stephen Holyday was elected in 2018 with 38.58% of the vote.

[18] Incumbent city councillor Mark Grimes was elected in 2018 with 40.90% of the vote.

[18] Incumbent city councillor Gord Perks was elected in 2018 with 44.55% of the vote.

[18] Incumbent city councillor Frances Nunziata was elected in 2018 with 32.18% of the vote.

[18] Incumbent city councillor Ana Bailão was elected in 2018 with 83.62% of the vote.

Cressy announced that he would not be seeking re-election and resigned effective April 30, 2022 to accept a position as vice-president of George Brown College.

She announced that she would not be seeking re-election and resigned effective May 4, 2022 to run in the provincial election.

[15] Buxton Potts pledged to act as a caretaker councillor and not run in the election.

He has represented Willowdale on North York and then Toronto city council since the 1990 municipal election.

[18] Incumbent city councillor Cynthia Lai was elected in 2018 with 27.02% of the vote.