The 2022 Towson Tigers football team represented Towson University as a member of the Colonial Athletic Association (CAA) during the 2022 NCAA Division I FCS football season.

They were led by 13th-year head coach Rob Ambrose, and played their home games at Johnny Unitas Stadium in Towson, Maryland.

[1] Ambrose was fired at the end of the season, and replaced with interim head coach Lyndon Johnson.

[2] Source:[3]