The men's quadruple sculls competition at the 2022 World Rowing Championships took place at the Račice regatta venue.

[1] The schedule was as follows:[1] All times are Central European Summer Time (UTC+2) The four fastest boats in each heat advanced directly to the AB semifinals.

[2] The three fastest boats in each heat advanced to the AB semifinals.

[4] The A final determined the rankings for places 1 to 6.

Additional rankings were determined in the other finals[5] [6]