[14] Justin Verlander, who had missed Houston's postseason runs in 2020 and 2021, made his return from Tommy John surgery and led the AL in wins, ERA, and walks plus hits per inning pitched ratio.

[15] Rookie shortstop Jeremy Peña won the League Championship Series Most Valuable Player Award after batting 6-for-18 (.333) with two home runs and two doubles in the ALCS.

Dombrowski is the first lead executive to make World Series appearances with four different teams, having done so with the Florida Marlins in 1997, Detroit Tigers in 2006 and 2012, and the Boston Red Sox in 2018.

[39] In the top of the tenth inning, Realmuto hit a solo home run off Luis García to give the Phillies a one-run lead.

In the bottom of the tenth inning, David Robertson struck out Yordan Alvarez before giving up a double to Bregman.

Nick Castellanos scored the first run for the Phillies on a sacrifice fly by Jean Segura in the seventh inning to make it 5–1.

In the top of the eighth inning, Kyle Schwarber hit a foul ball that was initially ruled a two-run home run, which would have made the score 5–3.

[47] Bernie Parent, Mike Schmidt, Julius Erving, and Brandon Graham threw ceremonial first pitches,[48] and Chloe Bailey sang the national anthem.

[51] In the bottom of the first, Kyle Schwarber drew a walk, and Bryce Harper hit a two-run home run to right field.

Connor Brogdon, Kyle Gibson, Nick Nelson, and Andrew Bellatti each pitched a scoreless inning to complete the shutout as the Phillies won 7–0.

José Alvarado relieved Nola and hit Yordan Alvarez with a pitch, scoring the game's first run and breaking a 16-innings scoreless streak for Houston.

[63] Philadelphia native Jazmine Sullivan performed the national anthem[64] and Brad Lidge threw the ceremonial first pitch to Carlos Ruiz.

[68] Jose Altuve led off the game with a double, advanced to third base on an error, and scored on a single by Jeremy Peña.

In the top of the eighth inning, Altuve scored from third base on a ground out by Yordan Alvarez, widening the Astros' lead to 3–1.

In the bottom of the eighth inning, Nick Castellanos scored on an RBI single by Jean Segura, narrowing the Phillies' deficit and putting runners on the corners.

Estimates from Nielsen Media Research showed the baseball game drew an average of five million more viewers, with a share of at least 50 in both Philadelphia and Houston.

[74] Gallery Furniture's Jim McIngvale threw the ceremonial first pitch, Andy Grammer sang the national anthem, and George Strait called "play ball!"

This was eventually broken by Kyle Schwarber hitting a solo home run to right field for the Phillies off of Valdez in the top of the sixth inning.

In the bottom of the sixth, Wheeler hit Martin Maldonado with a pitch, which he and J. T. Realmuto argued he leaned into akin to Aledmys Diaz's attempt in Game 1, though this time the umpire ruled in favor of the Astros.

Alvarado then gave up a three-run go-ahead home run to Alvarez, which flew 450 feet to center field and over the batter's eye.

[79] The Astros became the sixth team since 1960 to win the World Series after losing the previous year, with the last having been the Kansas City Royals in 2015.

For the 23rd straight year, the World Series was televised in the United States by Fox, including the local affiliates WTXF-TV in Philadelphia and KRIV in Houston.

[83] Davis was joined by Baseball Hall of Famer John Smoltz as color analyst, and Ken Rosenthal and Tom Verducci as field reporters.

Kevin Burkhardt hosted the pregame and postgame shows, joined by analysts Frank Thomas, Alex Rodriguez, and David Ortiz.

[88] Dave Flemming called the play-by-play of the games for Anglophone viewers, with Dan Plesac as color analyst.

Dan Shulman called the play-by-play, with Jessica Mendoza and Eduardo Pérez as color analysts and Buster Olney as field reporter.

This sponsorship included logo branding in-stadium and on official digital properties on the field, as well as commercial inventory during Fox's telecasts of the games.

ESPN's Jeff Passan covered the shocking departure, characterizing owner Jim Crane as extremely hands-on and at odds with Click's management style.

However, in the postseason, the Astros were beaten by the Rangers in the 2023 ALCS, with the visitor winning all seven games, similar to the 2019 World Series.

They would again defeat the NL East-winning Atlanta Braves in the NLDS before being upset by the Arizona Diamondbacks in the NLCS by losing the team's first ever game seven at home.