Teams from the fifth-level Belgian Division 3 or lower will begin in round 1, with the exception of sixteen teams from the Belgian Provincial Leagues which were randomly drawn to start in the preliminary round.
Furthermore, the eight non-professional teams left in the draw were always entitled to home-ground advantage, with the exception of Harelbeke, Meux and Elene-Grotenberge as their respective home grounds were not deemed suitable to host a cup match at this stage.
Most notable fixtures of the draw include a Clasico to be played between Anderlecht and Standard, the return of former captain Ruud Vormer to Club Brugge as they received his new team Zulte Waregem, and saw Knokke receive Oud-Heverlee Leuven.
Title holders Antwerp were paired at home to Charleroi, who have yet to win the cup.
With no amateur sides left, the draw was fully open as there were no seedings or predetermined home advantages.
The draw resulted in a "Battle of Flanders" between Gent and Club Brugge and a Brussels derby between Union SG and Anderlecht.