The team played its home games on Denny Crum Court at the KFC Yum!

Center in downtown Louisville, Kentucky as members of the Atlantic Coast Conference (ACC).

They went on a three-game losing streak from there, including an opening ACC game loss to Virginia Tech.

After their ACC tournament loss, the Cardinals fired head coach Kenny Payne.

California was the first such team to fall to 0–7, doing so on November 26, 2022; Louisville reached that mark three days later.