The Cardinals were led by seventeenth-year head coach Jeff Walz, and played their home games at the KFC Yum!

This season was their tenth year competing in the Atlantic Coast Conference.

Louisville started the ACC season with five straight wins to reach their highest ranking of thirteenth.

They defeated number 12 Notre Dame but lost to four ranked teams in that span, including a final day loss to then number 17 Notre Dame.

They received and at-large bid to the NCAA tournament and were the fifth seed in the Seattle 4 Regional.