The 2022 UNAF U-17 Tournament, which also served as the qualifiers for the Africa U-17 Cup of Nations, took place between 8 and 14 November 2022 in Algiers, Algeria.

The WAFU-UFOA Zone A qualifiers for the Africa U-17 Cup of Nations were hosted by Mauritania with the matches played between 1 and 9 October 2022.

The WAFU-UFOA Zone B qualifiers for the Africa U-17 Cup of Nations were hosted by Ghana with the matches played between 11 and 24 June 2022.

The UNIFFAC qualifiers for the Africa U-17 Cup of Nations were planned to be held in Cameroon between 7–12 January 2023 but was postponed and eventually played between 12 and 18 January 2023 due to a number of players being deemed overage by the MRI tests for Chad, DR Congo and Cameroon.

[16][17][3] The CECAFA qualifiers for the Africa U-17 Cup of Nations were hosted by Ethiopia, with the matches played between 2 and 19 October 2022.

However, on 26 September, Eritrea and Rwanda withdrew from the competition, leaving both the groups with four teams.

[5][6] On 1 October, Djibouti and Sudan were disqualified from the tournament after some of their players failed the MRI test, leaving Group B with only two teams.

The COSAFA qualifiers for the Africa U-17 Cup of Nations were played between 2 and 11 December 2022 in Malawi.

[20] However, South Sudan was disqualified from the tournament after 5 players failed the MRI test.