Arizona got off to a good start, scoring a run in the first inning on a Christian Walker single and another in the second on a Gabriel Moreno sacrifice fly.

Immediately in the bottom of the first, the Dodgers scored five runs on a sacrifice fly by Chris Taylor and a grand slam by Trayce Thompson.

However, a few batters later, Jake McCarthy came to bat with two outs and runners on second and third, and bunted for an infield single that scored the game-winning run as the Diamondbacks would close the door in the bottom of the ninth, winning the game 2-1 and splitting the opening series of the season.

The game would get off to a bad start for Nelson, as he would give up a two-run homer to Juan Soto in the first, and after the Diamondbacks tied the game in the top of the second on a Nick Ahmed RBI single and a Gabriel Moreno run-scoring double play, the Padres would break the tie again, on a Manny Machado RBI single.

Arizona would then get runners on the corners with one out, but fortunes turned against them as Gabriel Moreno would ground into an inning-ending double play, and in the bottom of the ninth, Scott McGough gave up a game-tying homer to pinch-hitter David Dahl and one batter later a home run to Ha-Seong Kim, winning the game for the Padres 5-4 in walk-off fashion.

Arizona would get one back in the fifth on a Josh Rojas sacrifice fly, but San Diego would respond in the bottom of the inning with a two-run homer by Xander Bogaerts.

In the eighth inning, the Diamondbacks would manufacture four runs as Jake McCarthy singled, stole second, moved to third on a groundout, and scored to tie the game on a Perdomo sacrifice bunt.

In the bottom of the eighth, Diamondbacks right fielder Jake McCarthy would make a running catch and fall into the stands for the third out of the inning.

In the top of the first, Mookie Betts's led off with a double, advanced on a passed ball, and scored on a J. D. Martinez sacrifice fly to give Los Angeles an early lead.

The Diamondbacks would tie the game in the third on a Corbin Carroll RBI single, but Los Angeles would retake the lead an inning later thanks to Chris Taylor's home run.

In the sixth, the Diamondbacks tied and then took the lead on back-to-back solo home runs from Evan Longoria, who was in the midst of a 3-for-3 performance, and Corbin Carroll, Arizona would extend their lead in the eighth as Nick Ahmed and Gabriel Moreno would both have RBI hits to solidify the Diamondbacks' first home win of the season.

[26][27][28] The Diamondbacks would again be working from behind as the Dodgers scored four in the first thanks to a Max Muncy RBI single, a J. D. Martinez sacrifice fly, and a two-run homer by James Outman.

In the third, the Diamondbacks would double their lead due to a Gabriel Moreno RBI single, but they would find themselves in a jam in the fourth as the Dodgers would load the bases before Mookie Betts drew a walk to make the score 6-5.