The 2023 Cal Poly Mustangs football team represented California Polytechnic State University, San Luis Obispo as member of the Big Sky Conference during the 2023 NCAA Division I FCS football season.

Led first-year head coach Paul Wulff, the Mustangs compiled an overall record of 3–8 with a mark of 1–7 in conference play, placing 11th in the Big Sky.

Cal poly played home games at Mustang Stadium in San Luis Obispo, California.

On July 23, 2023, during the virtual Big Sky Kickoff, the Mustangs were predicted to finish eleventh in the Big Sky by both the coaches and media.

[1] The Mustangs had one player selected to the preseason all-Big Sky team.