The team was led by tenth-year head coach David Archer and played its home games at Schoellkopf Field in Ithaca, New York.

After the conclusion of the season, Cornell athletic director Nicki Moore announced the removal of David Archer from the head coaching position and the appointment of defensive coordinator Jared Backus as his interim replacement.

On offense, lineman and team co-captain Micah Sahakian, quarterback Jameson Wang, and receiver Nicholas Laboy won second-team honors.

Cornell hosted Ivy League opponents Brown, Princeton, and Columbia, and traveled to Yale, Harvard, Penn, and Dartmouth.

[5] [6][7] Seeking to improve on a 5–5 record in 2022, the Big Red traveled to Lehigh University in Bethlehem, Pennsylvania, for its season opener on Saturday, September 16.

The Big Red defeated the Mountain Hawks 23–20, aided by two first quarter touchdown passes from quarterback Jameson Wang, first to Davon Kiser and then to Parker Woodring.

Cornell recovered Lehigh's onside kick with less than two minutes to play in regulation, leading 23–20, and was able to expend the remainder of the clock to secure its first victory of the season.

Meanwhile, the Big Red's Jackson Kennedy kicked a 22-yard field goal late in the second quarter, narrowing the deficit at halftime to 14–3.

With just under six minutes remaining in the fourth quarter, Cornell's Kennedy was again successful in a 22-yard field goal attempt, giving the Big Red a 20–14 lead.

[10] In spite of the victory, senior linebacker and team co-captain Jake Stebbins suffered a knee injury during the contest with Yale, ending his season.

[12] The Big Red returned to Schoellkopf Field in Ithaca, New York for homecoming and for its season home opener against rival Colgate University on Saturday, September 30.

With less than three minutes remaining in regulation, Wang threw an 11-yard touchdown pass to Cornell wide receiver Nicholas Laboy and followed with a two-yard rush for a successful two-point conversion, bringing the Big Red to within a field goal of tying the game, 28–25.

The Raiders defense, however, sacked Wang on the second play from scrimmage and forced a fumble, which Colgate recovered in Cornell's endzone for a touchdown and a 35–25 lead.

Second-string quarterback Luke Duby also made an appearance in Cornell's final possession, completing four of seven passing attempts for 35 yards.

[17] Following the defeat on the road against Harvard, the Cornell Big Red returned to Ithaca to conclude its season nonconference schedule against Bucknell University on Saturday, October 14.

The Big Red opened scoring in the second half, a 5-yard Jameson Wang touchdown run just over two minutes into the third quarter to take a 13–7 lead.

Bucknell added to the lead with the only points scored in the fourth quarter, a 6-yard touchdown pass with 9:15 remaining in the game to secure the 21–13 victory over Cornell.

[17] The Big Red remained at home on Saturday, October 21, defeating Ivy League opponent Brown University, 36–14, to improve to 3–3 overall and 2–1 in the conference.

The Big Red opened scoring with a 37-yard touchdown pass from Jameson Wang to Doryn Smith five-and-a-half minutes into the game to take a 7–0 lead.

Cornell expanded the lead to 14–0 early in the second quarter with a 7-yard Ean Pope touchdown run and added six more points in the first half resulting from two Jackson Kennedy field goals.

[19][20] The Big Red continued to build on the lead in the third quarter, opening second half scoring with another 37-yard touchdown pass, from Jameson Wang to Matt Robbert.

The Cornell defense followed on, cutting off the Brown Bears' ensuing offensive possession with a 55-yard Paul Lewis III interception return for a touchdown and a commanding 33–0 lead.

Brown did not score again, however, and Cornell recorded the only points of the fourth quarter, a 42-yard Kennedy field goal, to secure the 36–14 victory in the Ivy League matchup.

Neither team recorded any points in the second half of the game, exchanging punts in the majority of possessions, though Kennedy's field goal attempt with just over ten minutes remaining in the fourth quarter was unsuccessful from 47 yards.

[21] To begin its final road trip of the season on Saturday, November 4, the Big Red traveled to the University of Pennsylvania, its historical rival, in Philadelphia to contend for the Trustees' Cup awarded annually to the winner of the football matchup between the two schools.

These were the only points Cornell scored in the game, however, as the Big Red were unable to capitalize on its ability to move the ball down the field.

Cornell again drove into Penn territory on its next possession, this time to the 1-yard line, where the Big Red turned the ball over on downs after attempting a quarterback run on fourth-and-goal.

Cornell responded in the second quarter with a 5-play, 58-yard possession resulting in a 2-yard touchdown pass from running back Drew Powell to Ean Pope to close the Dartmouth lead to 14–7.

[25] For its final game of the season, the Cornell Big Red returned to Ithaca to face Ivy League rival Columbia University in the Empire State Bowl on Saturday, November 18.

Columbia continued to build on the lead, scoring four additional times in the second quarter to end the half ahead of the Big Red, 22–0.