The men's 110 metres hurdles event at the 2023 European Athletics U23 Championships was held in Espoo, Finland, at Leppävaara Stadium on 14 and 15 July.

[1] Prior to the competition, the records were as follows: Qualification rule: First 2 in each heat (Q) and the next 6 fastest (q) advance to the Semi-Finals.

[2][3] Wind:Heat 1: +1.6 m/s, Heat 2: -2.3 m/s, Heat 3: -1.7 m/s, Heat 4: 0.0 m/s, Heat 5: -1.4 m/s Qualification rule: First 3 in each heat (Q) and the next 2 fastest (q) advance to the Final.

[4][5] Wind:Heat 1: +0.3 m/s, Heat 2: -0.7 m/s [6] Wind: +0.5 m/s