[3] The regular season was paused from July 20 to August 19 for the month-long Leagues Cup, during which time MLS teams played Liga MX opponents.

[5] Fox Sports retained linear MLS TV rights, while for the first time in league history, ESPN no longer aired matches.

Univision opted to only air Leagues Cup games, thus also not broadcasting MLS regular season contests after a combined nineteen years.

[6] For the first time since its founding, MLS qualification berths for the 2024 CONCACAF Champions Cup were not exclusively allocated to American clubs, allowing expatriated Canadian clubs an opportunity to qualify for the tournament without necessarily winning the Canadian Championship.

[3][30] The regular season began on February 25 and culminated with Decision Day on October 21, where all teams (except D.C.) played each other in simultaneous intra-conference matches.

[3][31] The majority of matches were played on Wednesdays and Saturdays at 7:30 p.m. local time as part of the Apple TV+ streaming contract.