[4] Republicans Shane Quick (who ran against Hosemann in 2019) and Tiffany Longino also filed for the race,[3] as did Democrat D. Ryan Grover, a former candidate for the Oxford Board of Aldermen.

[3] In August 2023, Shuwaski Young withdrew his candidacy from the race for secretary of state, citing "a hypertensive crisis that was limiting his ability to campaign."

On September 7, the Mississippi Democratic Party nominated Ty Pinkins, an attorney and military veteran, as the replacement nominee for the November ballot.

[3] Democratic attorney and Disability Rights Mississippi Litigation Director Greta Kemp Martin ran to challenge Fitch.

[4][3] McRae faced a rematch in the general election, as former member of the Bolton Board of Aldermen Addie Lee Green was the only Democrat to announce a run.

[3][4] Republican Mitch Young, a former U.S. Navy Petty Officer and candidate for governor in 2015, announced a primary challenge against Chaney.

[19] No Democrats filed to run to succeed Presley,[19] leaving the field open for two Republican challengers to run for the open seat: Mandy Gunasekara, former Chief of Staff for the Environmental Protection Agency, was a challenger,[19] but she was removed from the ballot due to citizenship eligibility issues.

[4] Bailey's 2019 Democratic opponent, current state representative De’Keither Stamps, faced him again in a rematch.

[23] Republican state representative for the 111th District Charles Busby[22] ran against Independent Steven Brian Griffin.