The 84th annual edition of the tournament began on March 14, 2023, and concluded with the UConn Huskies defeating the San Diego State Aztecs, 76–59 in the championship game on April 3 at NRG Stadium in Houston, Texas.

Another school, Texas Southern, won the SWAC tournament to become the third 20-loss team to make the field, after the Coppin State Eagles in 2008 and Liberty Flames in 2013.

[4] Coincidentally, much like the previous time a top seed lost in Round 1, the regional final was contested between a mid-major (in this case Florida Atlantic) and Kansas State.

[5] Additionally, Princeton subsequently defeated Missouri in the second round to advance to the Sweet 16, marking the third consecutive year where a 15-seed reach the regional semifinals.

[8] This was also the first NCAA tournament in which all of the top seeds failed to make the Elite Eight, after Alabama and Houston's eliminations in the Sweet Sixteen.

FAU also became the first team since George Mason in 2006 to make the Final Four in the same season that it earned its first NCAA tournament win.

Of the rotation players on the Final Four teams (those receiving regular playing time), the highest-ranked in the composite recruiting rankings of 247Sports was UConn's Jordan Hawkins, who was #51 in the 2021 class.

The 2023 tournament was Jim Nantz's final season as the lead play-by-play announcer, with Ian Eagle succeeding him starting in 2024 onwards.

[31] In addition, the March Madness app offered Fast Break, whiparound coverage of games similar to NFL RedZone on the First weekend of the tournament (First and Second rounds).