[2][3] It officially began on 1 January 2023, with the start of the Adelaide International,[4] and ended 25 November 2023 after Serbia's defeat by Italy in the semifinals of the Davis Cup Finals.

[5] Djokovic defeated Stefanos Tsitsipas in the final, 6–3, 7–6(7–4), 7–6(7–5), to win his 10th Australian Open title and 22nd major overall, equaling Nadal's all-time record.

1 was on a roll, extending his winning streak to 15 matches before losing to eventual champion Daniil Medvedev in the semifinals of the Dubai Tennis Championships.

[6] In March, Djokovic withdrew from the Indian Wells Masters and Miami Open after being denied a visa into the United States due to being unvaccinated.

[15] In the quarterfinals, following a one hour rain delay at the end of the second set, Djokovic was defeated by eventual runner-up Holger Rune 6–2, 4–6, 6–2.

He became the first man to achieve a triple career Grand Slam, and became the oldest French Open champion at the age of 36 years and 20 days.

[19] This was Djokovic's first tournament in the United States since the 2021 US Open, following the lifting of COVID-19 vaccination requirements for international air travelers in May 2023.

[28] By reaching a 47th men's singles major semifinal, Djokovic surpassed Roger Federer's Open Era record.

[37] In the quarterfinals, Djokovic defeated defending champion Holger Rune in a rematch of the previous year's final.

[38] Djokovic also played in the doubles event with Krajinovic as a warm-up for the upcoming Davis Cup Finals.

[41] Djokovic then lost to Sinner in a third set tiebreaker, which ended his 19-match winning streak and marked his first loss since the Wimbledon final.

[42] Djokovic rebounded quickly, however, and played some of his best tennis of the season to defeat second seed Alcaraz in the semifinals and home favourite Sinner in the final—both in straight sets—to win a record-breaking seventh ATP Finals title.

[48] In the quarterfinals against Britain, Djokovic defeated Cameron Norrie in singles to take his nation to the semifinals for the second time in three years and become the outright most successful Serbian player in the history of the Davis Cup with 44 wins in the competition, moving him one ahead of Nenad Zimonjić.

[49] In the semifinals against Italy, Djokovic faced Sinner for the third time in 11 days, losing in three sets despite holding three consecutive match points.

[52] Djokovic then teamed up with Miomir Kecmanovic for the decisive doubles match, but lost to Lorenzo Sonego and Sinner, who thus became the first player to ever defeat him twice in the same day.