[1][2] The South American U-20 Championship returned after 4 years due to the COVID-19 pandemic forcing CONMEBOL to cancel the tournament in 2021.

[5] After twelve years, Brazil won the tournament again after finishing first in the final stage's group, which meant the twelfth title in their history.

Champions Brazil, runners-up Uruguay and the hosts and third place Colombia qualified for the 2023 FIFA U-20 World Cup and 2023 Pan American Games.

Defending champions Ecuador managed to reach the last berth for the 2023 FIFA U-20 World Cup after finishing in fourth place.

[9] That tournament ended up being canceled due to the COVID-19 pandemic, however, Colombia maintained its right to hold the South American U-20 Championship but in 2023.

[15] Portuguese referee João Pinheiro was replaced by his fellow countryman António Nobre.

If tied on points, tiebreakers would be applied in the following order (Regulations Article 21):[4] All match times are in COT (UTC−5), as listed by CONMEBOL.