The Huskies played their home games at Elliot Ballpark on campus in Storrs, Connecticut.

The team is coached by Jim Penders, in his 20th season at UConn.

The 2022 Huskies finished with a record of 50–16, the most wins in school history, 16–5 in the Big East.

They won the Big East regular season and Tournament titles and were seeded second in the NCAA College Park Regional, which they swept to advance to the Stanford Super Regional.

They were defeated two games to one in their second overall Super Regional appearance by number two overall seed Stanford.